Head of AIRR Sequencing / Senior Scientist
convergentresearch.org
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Posted on Friday, July 26, 2024
This is an exciting opportunity to join a fast-paced, growing Focused Research Organization (FRO) startup (currently in stealth). Head of Sequencing will conduct NGS-based experimental research and contribute to novel assay development in a dynamic, interdisciplinary environment. The successful candidate will develop high-throughput workflows and generate datasets from adaptive immune cells. Head of Sequencing will work closely with other top-tier experimental and computational scientists to create groundbreaking new insights into adaptive immunity.
Responsibilities
We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
Responsibilities
- Design, plan, and execute NGS-based assays in coordination with interdisciplinary science teams.
- Prepare DNA and RNA libraries from immune cells.
- Maintain high standards for sequencing quality and throughput by rigorously performing in-house QC checks and remaining current with industry best practices.
- Establish and optimize workflows, write and maintain SOPs for NGS assays, maintain sequencer uptime, and manage reagent inventory.
- Contribute to the development of novel NGS and multiomics assays and research, inclusive of experimental design.
- Collaborate effectively with computational, molecular biology, and translational researchers.
- Oversee junior research staff.
- Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.
- PhD in biomedical engineering, genetics, immunology or related field that relies on next-generation sequencing applications.
- 2-3 years or more of postdoctoral or industry experience, or equivalent.
- High proficiency with nucleic acid preparation from adaptive immune cells.
- Proven track record of custom library-preparation development for next-generation sequencing.
- Expertise with **AIRR-seq / BCR-seq**, scRNA-seq, and other NGS approaches.
- Strong organizational, time management, and communication skills.
- Experience with single-cell multiomics techniques (eg, CITE-seq, LIBRA-seq), long-reads, and/or proteomic antibody sequencing (Ab-seq). (strongly preferred)
- Familiarity with diverse next-generation sequencing technologies such as Pacific Biosciences, Oxford Nanopore, and/or Ion Torrent.
- Familiarity with diverse microfluidics, microwell, and microfluidics-free platforms.
- Experience with liquid handling automation for sequencing library preparation.
- Proficiency in custom protocol development.
- Experience with sequencing and/or multi omic assay development.
- Competence in R and/or Python (Scanpy, Seurat).
- Management experience (inclusive of research assistants or graduate students).
- Competitive compensation: $100,000 - $140,000 a year (salary commensurate with experience)
- Excellent medical, dental, and vision insurance
- Generous time off + paid holidays
- A supportive environment to learn and develop new skills
- An opportunity to participate in high-impact, fast-paced, cutting-edge, collaborative team science; contribute to curing disease; and work with leading experts from different fields
- Exciting location in the Soho area of Manhattan
We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
This job is no longer accepting applications
See open jobs at convergentresearch.org.See open jobs similar to "Head of AIRR Sequencing / Senior Scientist" PL VS.