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Animal and Tissue Preparation Technician

Eon Systems PBC

Eon Systems PBC

San Francisco, CA, USA
USD 74k-89k / year + Equity
Posted on Aug 27, 2025

Location

San Francisco

Employment Type

Full time

Department

Structure

Compensation

  • $74K – $89K • 0.018%

About us:

At Eon, we are at the forefront of large-scale neuroscientific connectomic data collection. Our mission is to enable the safe and scalable development of brain emulation technology to empower humanity over the next decade, beginning with the creation of a fully emulated digital twin of a mouse within the next two years.

Role

Collaborating with a diverse team, including product managers, researchers, and engineering departments, your role involves the handling of animals (mostly mice) and preparing tissue for researchers to processes and image. You will need to contribute to a pipeline that properly acquires, fixes and slices tissues.

Responsibilities

  • Administer anesthesia to animals and perform transcardial perfusions.

  • Slice tissue with minimal damage.

  • Optimize fixation conditions of tissue.

  • Inject viral labeling reagents.

  • Manage mouse colonies.

Skills and Qualifications

  • Extensive experience with tissue sectioning and preservation.

  • Familiarity with tissue processing techniques such as clearing and expansion, as well as tissue staining approaches.

  • Fundamental understanding of fixation chemistry

  • Fundamental understanding of fluorescence microscopy

  • Ability to perform surgeries and injections.

  • Experience handling rodents and managing colonies.

Key Projects

These are examples of projects that you would be working on when joining us:

  • Start the workflow for the structural mapping portion of the company pipeline

  • Investigating tissue slicing protocols that induce the least amount of damage to the tissue microstructure

  • Administering labels to animals to enable downstream staining of neural tissues

Salary and Benefits

  • Competitive salary and equity.

Compensation Range: $74K - $89K